What Is Major Depressive Disorder (MDD)?
There are several depressive disorder diagnoses in the DSM-5, but major depressive disorder (MDD) is the most common. Understanding this condition, its symptoms, and possible treatment options can be valuable if you think you or someone you love might be living with it.
What is major depressive disorder?
According to the World Health Organization (WHO), approximately 280 million people worldwide experience depression. It is also one of the leading causes of disability and is more common in women than men. However, this statistic may be due to the stigma men experience when seeking support.
What are the symptoms of major depressive disorder?
Depression often surfaces in the teens, 20s, or 30s. However, it can also happen earlier in childhood or later in middle adulthood. In some cases, people may experience a single period of depression in their lives.
Symptoms of major depression often don't come and go sporadically. Instead, they are experienced throughout the day, almost every day, for an extended period. When someone experiences a major depressive episode, they may have symptoms like fatigue, social isolation, feelings of worthlessness, and a general sense of hopelessness.
According to the National Alliance On Mental Illness (NAMI), other common symptoms of depression include the following:
- Intellectual impairment
- Physical impairment
- Sleeping too often or experiencing insomnia
- Feelings of anxiety and restlessness
- Slow movements and reflexes while speaking, moving, or thinking
- Difficulty remembering details
- Challenges with focusing, concentrating, or making decisions
- Emotional instability, sadness, or frequent crying
- Feelings of guilt
- Feelings of worthlessness
- Irritability and quick anger
- Loss of interest in previously enjoyed activities
- Appetite changes
- Suicidal thoughts and urges
The symptoms experienced during a depressive episode range from mild to severe. When the symptoms are mild, the individual may be able to focus somewhat on everyday tasks, not functioning to their total capacity. However, when experiencing severe symptoms, the individual might struggle to complete any activities, including work, household chores, social responsibilities, and self-care.
What causes major depressive disorder?
Major depressive disorder is a complicated mental illness and can have various causes. According to the National Center For Disease Control and Prevention, the condition may be caused by one or a combination of the following risk factors:
- Brain Chemistry: An imbalance of chemicals in the brain like dopamine and serotonin
- Genetics: A family history of depression or other mental illness or a history of another mental health diagnosis
- Biology: Noticeable physical differences in the brain
- Hormones: Hormonal changes during pregnancy or for other causes, like taking birth control
- Personality: Some personality traits, like neuroticism, may be more highly associated with depression and other mental illnesses
Some non-biological external factors may increase the chances of MDD, including:
- Substance use disorders
- Low self-esteem
- Traumatic experiences, including but not limited to abuse or neglect
- Medication
- Societal stigma due to an identity, like an LGBTQ+ identity
- A physical illness
- Chronic stress
- Grief due to a loss
If you are struggling with substance use, contact the SAMHSA National Helpline at (800) 662-4357 to receive support and resources. Support is available 24/7.
How is MDD diagnosed?
To receive an MDD diagnosis, speak to your doctor or a healthcare professional. The doctor may conduct a physical exam if you're looking to rule out a medical condition.
Once the doctor rules out a physical challenge, they may refer you to a mental health professional for a psychological evaluation. This evaluation can involve discussing your symptoms and behaviors and may include completing a questionnaire. If any of your family members have a history of mental illness, your therapist or psychiatrist might look at what type of mental illness these individuals were diagnosed with.
Once they have all the information, the mental healthcare professional may offer a diagnosis based on the criteria outlined in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), published by the American Psychiatric Association. Five or more symptoms of a depressive episode lasting at least two weeks are needed to diagnose MDD.
What is MDD with psychotic features?
Depending on your circumstances and symptoms, you might be diagnosed with a specific type of depression called MDD with psychotic features, also known as psychotic depression.
Psychotic depression is a subtype of MDD and can have severe symptoms. It can be essential to seek emergency medical attention when psychosis is present because it's an illness that a professional can best monitor.
When diagnosed with psychotic depression, you may have the above symptoms of MDD in conjunction with psychotic symptoms like a loss of reality. In addition to auditory or visual hallucinations, an individual might experience:
- Hypochondria
- Insomnia
- Physical immobility
- Anxious or agitated behavior
- A desire to harm themselves or others
MDD with psychotic features is divided into two types, including:
- Mood-Congruent Psychotic Features: With this condition, hallucinations or visions experienced by the client revolve around depressing themes. For example, the hallucinations might include guilt and worthless or a preoccupation with death.
- Mood-Incongruent Psychotic Features: With this condition, hallucinations are unrelated to the client's mood and may be contradictory to experiences of depression. The symptoms for this type of MDD overlap with schizophrenia and may be much harder to recover from.
When experiencing delusions, the individual might fully believe what they see or hear and may attempt to harm themselves or complete an impossible or risky task. For this reason, receiving immediate support and following a treatment plan may be crucial.
There is no scientific or medical reason why some people develop psychosis, but genetics and a family history of mental illness may be linked. Stress can also be a factor that leads to a chemical imbalance in the brain. Coping mechanisms for stress, such as exercise, meditation, and therapy, can help prevent and manage these imbalances.
How to treat MDD
There are several approved treatments for MDD, including the following:
- Psychotherapy: Cognitive-behavioral therapy (CBT), interpersonal psychotherapy (IPT), mindfulness-based cognitive therapy (MBCT)
- Antidepressant Medication: Consult a medical professional to determine the most effective medication for you
- Combination: Medication, therapy, and other psychological services received simultaneously
- Treatment-Resistant Approaches: If your depression is not responding to the above methods, you might be recommended for treatment-resistant options like transcranial magnetic stimulation (TMS) for depression
Treatment for depression is often highly effective, although it may take six weeks or more to see results. However, some people struggle to reach out for help due to a personal choice, the stigma of mental illness, or a lack of resources, trained providers, and care.
When left untreated, depression can lead to other serious complications, including physical health complications and difficulty maintaining relationships with family and friends, leading to loneliness.
Counseling options
It is not your fault if you have been diagnosed with depression or believe you may be living with this condition. Depression can affect anyone at any stage of life, and you can reach out for support anytime. Depression is one of the most manageable and treatable mental illnesses for many, and with a combination approach to treatment, many clients find symptom remission.
If you're ready to start treatment, consider online therapy. Some people with depression find it challenging to get out of bed, and driving to a therapist's office might seem overwhelming. With online therapy through a platform like BetterHelp, you can attend treatment sessions from the comfort and safety of home. In addition, on the days you're not feeling up to therapy, you can choose between phone, video, or chat sessions, allowing you to chat with your therapist through messages instead of opening up a call.
Research shows that online therapy is effective, too. One study concluded that online therapy resulted in "clinically meaningful improvements in depression and anxiety scores relative to a baseline observed post-intervention at 12 weeks and sustained at program month six."
Takeaway
Is MDD the same as depression?
The term “depression” often refers to a mental health condition called major depressive disorder (MDD). However, it can also be used to describe disorders like postpartum depression, persistent depressive disorder, and seasonal affective disorder.
Is MDD a psychiatric illness?
Major depressive disorder (MDD) is a psychiatric illness. As with other forms of psychiatric illness, MDD affects an individual’s thoughts, feelings, and behaviors. MDD is one of several depressive disorders—a category of mood disorders primarily characterized by depressed mood, fatigue, and loss of interest in activities.
What are 5 MDD symptoms?
According to the Diagnostic and Statistical Manual of Mental Disorders—which is often used to diagnose depression—symptoms of major depressive disorder include low mood, anhedonia (loss of pleasure or interest in activities), weight gain/loss, sleep disruptions, and restlessness. There are several other symptoms that may accompany these five, though. If you believe you’re living with depression, your healthcare provider may provide you with screenings, ask about your medical history, and administer other assessments to determine whether your symptoms meet the criteria for MDD.
What causes MDD?
As with other forms of depression, major depressive disorder is thought to be caused by a mix of factors, which can include genetics, alterations in brain structure and function, environmental influences, and comorbid mental health or medical conditions.
Can MDD be cured?
While there is presently no cure for major depressive disorder, depression symptoms can be managed so that their impacts are limited. Many people who receive treatment no longer meet the diagnostic criteria for major depression. The most common types of treatment for depression are psychotherapy and medication.
Psychotherapy can help those with MDD address the emotional challenges of depression, identify sources of their feelings, and work through comorbid mental health concerns. Medication—such as selective serotonin reuptake inhibitors (SSRIs)—are also considered effective for alleviating symptoms of depression. For those with severe major depression, electroconvulsive therapy and other brain stimulation therapies may be utilized.
Is MDD a type of bipolar?
Major depressive disorder (MDD) is not a type of bipolar disorder, though bipolar disorder is also characterized by symptoms of depression. Bipolar disorder can feature episodes of depression; but it also typically features episodes of mania, which are marked by an elevated—as opposed to a low—mood.
How do people with MDD feel?
The symptoms that typically accompany major depressive disorder often cause people to feel sad, tired, irritable, or lethargic. An individual experiencing MDD may have feelings of hopelessness, worthlessness, or guilt. Often, people with depression also experience unexplained physical pain.
How long can MDD last?
For a depression diagnosis, an individual’s symptoms must have persisted for at least two weeks. However, depressive episodes may last for months or years, in some cases. The duration of the disorder can vary depending on the individual, their treatment plan, and whether they’re experiencing mild, moderate, or severe depression.
How rare is MDD?
Major depressive disorder is one of the most common mental health conditions, affecting an estimated 18% of adults in the US at some point in their lives. Anxiety disorders are the only category of mental illness more prevalent than depression.
- Previous Article
- Next Article