Can Alzheimer’s be inherited?

Alzheimer’s disease is a form of dementia, which affects behavior, thinking processes, and memory. The condition is typically found in those 65 and older but can develop earlier. Alzheimer’s is a progressive condition that worsens over time, and at present, there is no cure. Symptoms are usually managed with medications. Some signs of Alzheimer’s include:

• Loss of recent memory, forgetting important dates, repeating questions, and relying on memory aids like calendars or notepads.
• Difficulty planning and solving problems like trouble following a recipe or balancing a checkbook, or tasks like these taking longer than they did before
• Trouble finishing familiar or daily tasks like traveling to a familiar place such as the grocery store
• Confusion about time and place, like what day it is or being unable to follow the passing of time
• Difficulty with spatial relationships and visual images, like trouble determining distance which can cause safety issues when driving
• Problems with words, joining a conversation, repeating themselves, or recalling vocabulary
• Losing objects and being unable to retrace steps to find them
• Poor judgment and decision making that interferes with hygiene or poor money management
• Refusal to engage in once enjoyed social activities because of difficulty with remembering things, recalling words, or having a conversation
• Mood and personality changes that aren’t in line with the way a person once was

Research indicates that people who have a close relative, such as a parent or sibling with Alzheimer’s, have an increased chance of developing the disease than those without a close relative. But family history isn’t necessary for an Alzheimer’s diagnosis, and genetics aren’t the only factor in play for the development of the disease.

Scientists believe that there is genetics that plays a role in Alzheimer’s. Some genes indicate a risk of developing the disease but are not a guarantee that it will occur. Deterministic genes or a ‘guarantee’ of diagnosis have been identified but occur very rarely. Testing for both gene types is available, but at present, medical professionals don’t suggest routine testing for these genes as there are no cures available for Alzheimer’s nor proven methods for slowing its progress, so genetic testing doesn’t have an effect on treatment or prognosis.

If you’re noticing symptoms of Alzheimer’s in someone you love or in yourself, talk with your doctor as soon as possible. Early detection means early treatment of symptoms, which can be helpful to lengthen the amount of time that you or your loved one remain independent. You can also contact the Alzheimer’s helpline at 1-800-272-3900.