St. John’s Wort: Depression Treatment Options
When it comes to assessing natural remedies and alternative medicine, it can be challenging to determine what is safe and what works. Many of these substances have not been researched adequately, and they are often not approved by the Food and Drug Administration (FDA). On the other hand, many people have doubts about modern medicine and may prefer natural remedies. If you are from the latter school of thought and live with depression, you might consider some of these alternatives, such as St. John's Wort. You can usually find it in the supplement aisle of many supermarkets.
According to the National Center for Complementary and Integrative Health, St. John's Wort is a wild plant that grows in parts of Europe and Asia. The plant is cultivated, the flowers are dried, and then the product is packaged into capsules or processed into oils. The active ingredients are thought by some to relieve symptoms of depression, but research results have been mixed.
Below, we’ll weigh the pros and cons of using St. John's Wort. Before you use this information to aid in your decision to consider using St. John's Wort, it may be best to consult with a physician and mention any medications you take.
St. John's Wort: The potential benefits
A few clinical trials have suggested that St. John’s Wort can effectively reduce the symptoms of mild depression. In some studies, the supplement’s effects were observed to be greater than that of a placebo but not by a wide margin.
Some people may consider taking a natural supplement such as St. John’s Wort to avoid the side effects of some antidepressants. For example, some antidepressant medications have been known to cause a few side effects, such as a reduction in sex drive. Some people believe they might avoid this effect by taking St. John's Wort to treat symptoms of depression. This may be true for some people, but there is no guarantee that St. John’s Wort will reduce depression symptoms.
One other potential benefit of St. John’s Wort is that people who take it for depression may be more willing to commit to treatment than they would be if they were taking antidepressants. This could be due to various reasons, such as insurance hurdles or other financial stressors. Since treatment efficacy often depends on an individual’s adherence to the treatment, St. John's Wort may have an advantage in this sense.
St. John's Wort: Potential disadvantages
Also, studies show that St. John’s Wort can interact with other medications, including antidepressants. Combining these substances in your body can cause your brain's serotonin levels to rise to potentially fatal levels—a condition known as serotonin syndrome. This can lead to high blood pressure and an increased heart rate, among other symptoms.
If you take medication for depression or any other condition, it may be helpful to discuss St. John’s Wort with a physician before taking it.
St. John's Wort: Potential side effects
While the side effects are reported to be fewer than with antidepressants, this may not be the case for everyone. Some people report bouts of insomnia, nausea, and skin irritation. Everyone's body chemistry is different. Thus, there may be variance in the ways people react to treatment. This can also be true of antidepressant medications. If you are choosing this alternative option as a means of avoiding the potential side effects of antidepressants, it may be important to remember that both can produce side effects.
Also, some people who have taken St. John’s Wort have reported experiencing withdrawal symptoms once they stop. These can range from mild nausea to anxiety. As with any other form of treatment, it may be best to consult a physician before making any changes. A physician may advise you to wean off the supplement gradually rather than quit cold turkey.
St. John’s Wort hasn’t been thoroughly studied for treating severe depression. In many clinical trials conducted, the effects have only been shown to help those with mild to moderate symptoms. If you are experiencing severe depression or suicidal thoughts,* it’s recommended that you reach out for help immediately.
*The 988 Suicide and Crisis Lifeline can be reached at 988 and is available 24/7. There is also help available via chat at the lifeline’s website.
What should I do?
As with many mental health conditions, medication is not the only treatment available. Many people have benefited from various forms of therapy for depression. If your symptoms make it difficult to leave home for traditional therapy, you may benefit from online therapy, which numerous studies have shown to be just as effective as in-office therapy, including for depression.
Online counseling with BetterHelp
BetterHelp is an online counseling platform that can connect you with a therapist who specializes in treating depression. With online therapy, you can speak with a therapist via phone, live chat, or videoconferencing. You can also contact your counselor at any time through in-app messaging, and they’ll respond as soon as they can. This may be especially helpful if you experience symptoms in between sessions and want to write down what you’re feeling in the moment rather than waiting until your next session.
The efficacy of online counseling
Research has shown that online therapy can be just as effective at reducing symptoms of depression as traditional in-office interventions. In a review of six decades of clinical studies, researchers found strong evidence for “the safety and clinical effectiveness of administering evidence-based psychotherapy for anxiety and depression via clinical videoconferencing among heterogeneous populations and age ranges, and in multiple care settings, with similar outcomes to in-person care.” They found that the videoconferencing intervention was feasible, acceptable, and safe in numerous settings.
Takeaway
St. John’s Wort is a natural plant that some people take for depression. Studies on this supplement have yielded mixed results, and it has not been approved by the FDA. St. John’s Wort can produce dangerous side effects when combined with antidepressants, so it is recommended that you consult a physician before deciding to take it.
If St. John’s Wort and other treatments do not help you find relief from your depressive symptoms, it may be helpful to speak with a licensed therapist, whether in person or online. With BetterHelp, you can be matched with a licensed counselor who has knowledge of St. John’s Wort and experience helping people with depression. Take the first step toward learning about treatments for depression, and reach out to BetterHelp today.
Is St. John's wort safe for depression?
You should always talk to your doctor before trying St. John’s wort for depression, as it can interact with various medications with potentially dangerous effects. For example, taking St. John’s wort alongside certain prescription antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), may result in a harmful increase in serotonin.
In addition, St. John’s wort can weaken the impact of certain medications, such as birth control pills, antidepressants, some pain medications, and some blood thinners.
It’s also important to note that St. John’s wort can cause side effects like upset stomach, headache, fatigue, and confusion. Some have also reported sexual dysfunction after discontinuing the use of St. John’s wort.
When taking St. John’s wort, depression symptoms may be reduced, but this is not generally a healthcare provider’s first choice when treating major depression. Because St. John’s wort interacts with so many other medications, particularly birth control, it’s not the right choice for many people.
What does St. John's wort do for mood?
Research contains mixed results when it comes to St. John’s wort’s effects on mood. In some studies, it performed better than the placebo, and in others, there was no difference when it came to St. John’s wort versus placebo. St. John’s wort may improve mood in some people, but it’s vital to speak to your doctor before adding it to your regimen.
Does St. John's wort work with anxiety and depression?
A 2022 literature review stated that St. John’s wort “has shown to be comparable if not more efficacious than most standard treatment options for depression.” However, the review went on to explain that more research is needed, and it cannot yet be said that St. John’s wort is an appropriate replacement for current moderate depression and major depression treatment options.
Less research has focused on the possible effects of St. John’s wort on anxiety. There doesn’t seem to be much support for its use as a potential anxiety treatment at this time.
What is St. John's wort used for?
Some of the proposed uses for St. John’s wort include depression, ADHD, symptoms of menopause, OCD, and somatic symptom disorder. St. John’s wort might treat depression and other disorders, but more research is needed.
Is it safe to take St. John's wort every day?
St. John’s wort is generally considered safe to take in appropriate doses for up to 12 weeks. However, because it can interact with many different medications, it’s crucial to talk to your doctor before trying St. John’s wort.
Is it okay to take St. John's wort?
Whether or not it is okay to take St. John’s wort varies by individual. Be sure to speak to your doctor if you’re interested in trying this dietary supplement.
Will St. John's wort make me happy?
It’s possible that St. John’s wort may increase serotonin and contribute to happiness, but studies reveal mixed results. More research is likely needed as far as St. John’s wort’s effects on mild to moderate depression, major depressive disorder, and seasonal affective disorder.
Will St. John's wort relax me?
More research is needed regarding the efficacy of St. John’s wort for relaxation and the relief of anxiety symptoms.
Is St. John's wort good for stress?
At this time, there isn’t sufficient research to determine whether St. John’s wort may be an appropriate treatment for stress.
Is St. John's wort good for stress and anxiety?
More research may be needed when it comes to the effectiveness of St. John’s wort for stress and anxiety. Always speak to your doctor before adding dietary supplements to your regimen, as drug interactions may occur.
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