Do Dopamine Supplements Really Work?

Dopamine is generally defined as a neurotransmitter involved in a variety of brain functions, particularly the facilitation of feelings of pleasure. Dopamine supplements typically include ingredients that may facilitate dopamine production or help your body use dopamine more efficiently. Common dopamine supplements can include L-tyrosine, Mucuna pruriens, L-theanine, and Rhodiola rosea. Foods containing tyrosine, such as almonds, turkey, and bananas, may also affect dopamine levels. While supplements can be helpful for some people, it can be best to speak to a medical or mental health professional to determine the best treatment options for you.

You can connect with a licensed therapist in your local area or through an online therapy platform. BetterHelp now offers psychiatry services through UpLift as an additional care option alongside therapy when psychiatric support may be helpful.

*Medication is prescribed only when clinically appropriate and is not guaranteed. Pricing, availability, insurance coverage, and copays vary by plan, location, and provider availability are not guaranteed.

Dopamine: What it is and how it can affect you

Neurotransmitters like dopamine typically facilitate everything your brain does by carrying the chemical signals that drive your physical functions. From the involuntary breaths you take to the pleasant feelings you get when seeing loved ones, you can generally thank the neurochemicals in your brain for delivering the message. However, signals can get crossed when your brain chemistry becomes imbalanced, and you may experience upheaval in multiple areas of your life.

According to a recent study, dopamine typically plays a role in behavior, motivation, cognitive function, punishment and reward, voluntary movement, sleep, working memory, attention, and learning. Dopamine, along with serotonin, oxytocin, and endorphins, is frequently called a “happy hormone” due to its role in facilitating feelings of pleasure.

Low dopamine levels

A dopamine deficiency may not cause physical or mental health conditions on its own. However, it may indicate a problem. Some common symptoms of low dopamine levels can include low energy or sex drive, weight changes, tremors, constipation, mood swings, muscle cramps, hallucinations, loss of balance, and difficulty sleeping. You may also feel anxious, isolated from others, emotionally incapable, forgetful, or inattentive. Some people with dopamine deficiency also experience stomach troubles and difficulty with coordination.

High dopamine levels

While high dopamine levels in your brain can lead to an energy boost and positive emotions like confidence, an overabundance of dopamine can have adverse effects. When your dopamine rises too much, you may experience aggression, an inability to sleep, restless energy, an overactive sex drive, euphoria, and impulsivity.

Mental health conditions potentially related to dopamine

Substance use and dopamine levels

According to studies regarding brain scans of people with substance-related concerns, substance use can increase dopamine levels. A 2007 study found that the rate, speed, and intensity of dopamine increase often correlated with symptom severity.

Depressive disorders

Recent studies show a potentially significant connection between dopamine levels and anhedonia (the inability to take interest or pleasure from activities) in people with major depressive disorder.

Parkinson’s disease

Neurodegenerative diseases like Parkinson’s usually destroy the brain’s nerve cells, often preventing the healthy distribution and use of neurochemicals. Dopamine levels have generally been linked with Parkinson’s.

Attention-deficit/hyperactivity disorder (ADHD)

Studies show a potential link between differences in the brain’s dopaminergic system and reward behaviors for people with ADHD.

Schizophrenia

According to a recent review of medical journals, dopamine abnormalities in the prefrontal brain have frequently been seen in patients with schizophrenia.

What is a dopamine supplement?

Dietary supplements are generally products meant to help you replenish the things your body may be lacking, so they often contain ingredients like minerals, herbs, amino acids, enzymes, or other components to help improve your overall well-being or manage various health conditions.

Dopamine supplements may help your body produce more of the neurotransmitter or allow your body to use it more efficiently. Because several nutrients can affect how dopamine works, food and dietary supplements may substantially impact your brain’s neurochemical production. Always speak to your doctor before adding any type of supplement or medication to your regimen.

How do dopamine supplements work and affect brain function?

Dopamine supplements typically do not contain neurochemicals but rather other substances that can stimulate the brain’s production or how it is reabsorbed. While medications may directly target dopamine receptors, supplements typically use the body’s response to the ingredients to support dopamine-related functioning and overall neurochemical balance.

Do dopamine supplements work for mental health?

To correctly answer whether dopamine supplements work, you must first define what it means for a dietary supplement to “work”. If your definition is helping your body produce more dopamine, the answer is likely yes. However, if your parameters include effectively treating depression, mood disorders, or chronic dopamine deficiency, that can be a much more complicated answer.

It’s essential to recognize that supplements can support, but may not replace, professional treatment for mental health conditions. As shown below, multiple studies have indicated that dopamine supplements can be effective aids to overall well-being or specific health goals for some people. If you think dopamine supplements might be a good option, talk to your healthcare provider to discuss which ingredients are most likely to benefit your situation.

Supplement vs. medication: What’s the difference?

Dopamine-related medications may affect how the neurotransmitter functions in the brain. These prescription medications can stimulate (agonists) or reduce (antagonists) dopamine activity in your brain or block its reabsorption (reuptake inhibitors) by your nerve cells, potentially affecting dopamine levels. Medication decisions are individualized and should be made by a licensed medical provider based on a full evaluation.

• Dopamine agonist drugs may be used in the treatment of conditions such as Parkinson’s disease and restless legs syndrome, and in some cases may be considered for other health needs based on provider evaluation.
• Dopamine antagonists may be used in the treatment of schizophrenia and bipolar disorder, and they have also been used to treat nausea and vomiting.
• Dopamine reuptake inhibitors may be used in the treatment of narcolepsy, depression, and binge-eating disorder in some cases, based on a provider’s clinical judgment.

Supplements do not usually require a prescription, and they tend to work by activating the body’s natural response to the included ingredients rather than working directly with your brain chemistry as medications typically do. Supplements may offer less intense side effects and results that usually aren’t as pronounced.

Common dopamine supplements

While not an exhaustive list by any means, below are some common dopamine supplements.

L-tyrosine as an amino acid supplement

In a recent review of the medical literature, patients reported that the supplement usually prevented a drop in cognitive function as a response to physical stress, such as involuntary reactions to cold, extended wakefulness, or high altitudes.

While many may link L-tyrosine to stress relief, science shows it may be more likely to prevent loss of mental ability due to physical stressors, which may have little practical application for most people but significant value to the military and those needing to increase dopamine production under stress.

Mucuna pruriens as a dopamine supplement

The powdered version of the Mucuna pruriens plant has often been used in traditional Indian medicine for centuries as a natural source of levodopa (the precursor to dopamine), and it is frequently used as a complementary approach in research related to Parkinson’s disease. Research shows many possible uses for the supplement with a wide array of potential benefits.

“Mucuna pruriens is an established herbal drug used for the management of male infertility and nervous disorders, and also as an aphrodisiac. It has been shown that its seeds are potentially of substantial medicinal importance,” said the authors of a paper about the supplement’s benefits.

L-theanine and dopamine supplements for cognitive enhancement

Recent behavioral studies suggest that the amino acid L-theanine, which is typically found in green tea, may have neuropharmacological applications to improve learning and memory while exerting neuroprotective effects on the brain.

A 2021 study replicated the attention-boosting benefits, showing the potential to enhance working memory and improve executive function.

Rhodiola rosea to increase dopamine levels

This dopamine supplement generally comes from the Rhodiola rosea plant, also called rosenroot or golden root. It has frequently been used as a Chinese medicinal herb for centuries. According to a recent study, Rhodiola extract may have antioxidant, anti-aging, anti-cancer, and neuroprotective qualities in addition to a significant ability to mitigate stress responses.

Dopamine-influencing vitamins and ingredients

A wide array of dietary supplement ingredients may also play a role in dopamine support, potentially helping to reduce symptoms of depression or improve mood. These ingredients can include vitamin C, fish oil, magnesium, turmeric, vitamin D, probiotics, and saffron extract.

Foods thought to boost dopamine production can include almonds, turkey, avocados, bananas, yogurt, soy products, fish, cheese, milk, and chicken, primarily due to their natural levels of tyrosine.

Natural ways to balance dopamine

• Get plenty of sleep
• Exercise regularly
• Listen to music, meditate, or participate in other enjoyable activities
• Eat a balanced diet, including probiotics
• Get some sun (with sunscreen)
• Practice a mindful lifestyle

How a therapist can help you treat a chemical imbalance

Though therapy may not directly manage your neurotransmitters, working with a licensed therapist can help you explore whether you’re experiencing symptoms that may be related to dopamine or another mental health concern. A therapist can help you identify supportive next steps, which may include discussing supplements with a medical provider. Many people have found online therapy through virtual providers like BetterHelp a convenient and practical option.

Users frequently report lower costs, reduced wait times, and increased convenience since they can receive treatment from home. BetterHelp now offers psychiatry services through UpLift as another option for people who may benefit from psychiatric evaluation or medication management when clinically appropriate. Medication availability and coverage may vary by member location, clinical appropriateness, and individual pharmacy/insurance benefits. Prescribing decisions are made by the treating clinicians. We do not guarantee that any specific medication will be prescribed or covered by a member’s insurance plan.

Recent studies show that online cognitive behavioral therapy (CBT) can be an effective and convenient alternative to treatments in the traditional clinical setting. Online CBT has frequently been used to help patients identify and correct harmful or unhelpful behaviors and thought patterns and develop a repertoire of functional coping skills to manage stress.