Genetics And Alcohol Use Disorder: Is Alcoholism Genetic?

Medically reviewed by Dr. April Brewer, DBH, LPC
Updated July 1st, 2025 by BetterHelp Editorial Team

Questions about why some individuals develop problematic drinking patterns while others do not have been circulating for decades. Researchers continue to examine the potential links between biology, environment, personal experiences, and alcohol use disorder (AUD). Among the many questions being studied, one of the most persistent is whether alcoholism may have genetic origins. Although no single cause has been found, some evidence suggests that certain influences, both genetic and otherwise, may play a role in shaping how a person responds to alcohol consumption.

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Recovery from alcohol use disorder is possible

Understanding alcoholism

Alcoholism, more formally recognized as alcohol use disorder, is described in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) as a condition in which a person has difficulty managing or stopping drinking alcohol, even when it causes harm. The challenges associated with AUD can affect emotional, physical, and social well-being. While alcohol use disorder (AUD) is often discussed in terms of behavior or habits, research suggests that its roots may extend further into biological and environmental factors.

AUD exists on a spectrum, ranging from mild to severe, and may look different depending on individual experiences and circumstances. Some may encounter difficulty with alcohol misuse during times of stress, while others might find themselves developing dependence over time due to a blend of underlying risk factors.

The development of alcohol use disorder

The development of AUD is not always straightforward. Efforts to pinpoint contributing elements have drawn researchers toward multiple areas of study, from personal psychology to genetic factors. These inquiries don’t aim to label individuals but rather to provide insight into possible patterns that might help with early detection and prevention.

Current research suggests that multiple variables, including emotional history, coping mechanisms, and exposure to environmental factors, might interact in subtle and varied ways. These elements, when taken together, could influence a person’s relationship with alcohol. It remains unclear exactly how strong each factor is. However, growing evidence points to a combined influence of internal and external contributors.

What causes alcohol use disorder?

Pinpointing a single cause of AUD remains difficult. Researchers and clinicians often look at several overlapping elements when trying to understand the development of this condition. These may include individual personality traits, family background, mental health conditions, and life events.

Is alcoholism genetic?

Some scientific investigations indicate that genetic makeup might contribute to a person’s likelihood of developing AUD. Specific genetic variants, such as those found in genes labeled ADH1B and ALDH2, are thought to influence how the body processes alcohol. These genes are related to alcohol metabolism, a function that can influence how alcohol affects the body and mind.

In large-scale genetic studies, researchers have found that certain families may share inherited patterns that increase susceptibility to alcohol dependence. While it's estimated that genetics could account for roughly 40% to 60% of the risk, this does not mean that anyone with a family history of AUD will automatically face the same outcome. 

The presence of an “alcohol addiction gene” is not necessarily predictive on its own. However, when combined with certain environmental factors, it may increase the chance of a person developing AUD.

Environmental and psychological influences

Beyond genetics, external conditions seem to play a key role in shaping alcohol-related behavior. Growing up in a home where alcohol misuse is normalized or frequently modeled might influence early exposure and long-term habits. Factors like peer pressure, job-related stress, and lack of emotional support may also interact with underlying vulnerabilities.

Psychological factors, including a history of trauma, poor impulse control, and mental disorders like anxiety or depression, have been noted in many individuals who have trouble managing their alcohol consumption. These influences can act either independently or in conjunction with genetics, making each person’s risk profile highly individual.

What science says: Studies linking genes and alcoholism

Over the past several decades, researchers have made strides in identifying biological traits that may contribute to AUD. These findings are not yet conclusive but offer potential paths toward understanding how genetics and behavior intersect.

Genetic markers linked to alcohol use disorder

In efforts to pinpoint potential hereditary markers, scientists have explored a variety of genetic studies involving large populations. Several genes, including CHRNA5 and GCKR, have been examined for an association with behavior and substance use. Some of these genes are thought to be involved in how the brain’s reward system responds to stimuli, including alcohol.

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Alcohol metabolism and tolerance

Another area of interest lies in alcohol tolerance genetic traits. One of the more frequently cited genetic markers in alcohol-related studies is alcohol dehydrogenase, an enzyme responsible for breaking down alcohol in the body. 

Variations in this gene may influence how quickly alcohol is metabolized, possibly altering how pleasurable or aversive the effects of alcohol are for different people. Some people seem to need larger quantities of alcohol to feel its effects, often referred to as an increased alcohol tolerance. Over time, this may contribute to drinking larger amounts, which could lead to dependence in some cases.

The role of genetic factors in prevention and early intervention

Understanding possible genetic factors behind AUD can offer value when considering prevention strategies. If someone is aware that they may carry certain traits linked to alcohol dependence, they might be more inclined to make mindful decisions about drinking.

Preventive measures might include having earlier conversations with healthcare providers, self-monitoring, or pursuing counseling before potentially problematic habits develop. Early recognition, paired with increased mental health literacy, could potentially reduce the chances of developing a more serious problem.

Professionals may also use screening tools like the alcohol use disorders identification test (AUDIT) to detect early signs of risky drinking behavior. When used thoughtfully, these tools can identify patterns that may require closer attention, especially in those with known familial or personal risk factors.

Mental health strategies for alcohol use disorder 

Addressing AUD often requires more than simply reducing alcohol consumption. Because the condition may involve psychological or emotional dimensions, an integrated mental health approach could be beneficial.

This type of approach typically involves exploring the individual’s motivations for drinking, the role that alcohol plays in their life, and how it intersects with other concerns, like anxiety, depression, or trauma. Rather than relying solely on behavioral control, therapy and evidence-based treatment strategies tend to emphasize long-term emotional support and insight.

Education, awareness, and recovery

Promoting awareness of the many influences contributing to AUD can create a more supportive and less judgmental environment. Education often plays a crucial role, not only for individuals living with AUD, but also for their families, friends, and communities.

Efforts to reduce stigma and increase access to accurate information may allow more people to seek help. Building protective habits, such as engaging in fulfilling activities, cultivating strong relationships, and accessing professional support, can serve as helpful tools in recovery and prevention.

How therapy can help

Psychological therapy remains one of the most widely recommended approaches to managing and understanding AUD. Whether a person’s concern is rooted in behavior, emotion, or both, talking with a mental health provider can offer space to unpack those experiences. Modalities like cognitive behavioral therapy (CBT), motivational interviewing, and trauma-informed approaches can help individuals explore the deeper reasons behind their alcohol use and work toward healthier coping strategies. 

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Recovery from alcohol use disorder is possible

The mental health benefits of online therapy

Online therapy may provide a convenient, accessible, and affordable option for those seeking mental health support, particularly for individuals with demanding schedules or limited access to in-person services. While more research is needed regarding the effectiveness of online therapy for treating AUD, studies suggest that virtual sessions can offer benefits similar to traditional face-to-face therapy, with many people reporting meaningful improvements in emotional health and symptom management for conditions like anxiety and depression. 

By removing common obstacles, such as travel time and geographic limitations, online therapy may make it easier for individuals to maintain regular contact with their therapists, potentially supporting greater consistency and longer-term progress. The ability to choose between video, audio, and online chat sessions on platforms like BetterHelp can also contribute to increased comfort levels throughout the therapeutic process.

Takeaway

Alcohol use disorder appears to involve a combination of biological, psychological, and environmental factors. Although some individuals may carry genetic variants that influence their response to alcohol, the presence of such a risk factor does not guarantee the development of AUD. By supporting early education, increasing access to mental health care, and encouraging thoughtful self-reflection, more people might find effective ways to navigate their relationships with alcohol. While there are still many questions to answer, taking the steps to understand AUD can bring us closer to developing compassionate, informed, and individualized approaches to care. If you struggle to manage your alcohol consumption, consider seeking professional help in person or online.
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